Small molecules which reverse ATM knockout
Canned Analysis
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General Information
AccessionDCA00021318
TitleSmall molecules which reverse ATM knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ATM knockout in the MEFs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fa8fe467bea600fb9f18
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1902
Cell TypeMEFs
Gene Symbol (human)ATM
Gene Symbol (mouse)Atm
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM569459, GSM569461, GSM569463
Perturbed SamplesGSM569465, GSM569467, GSM569469
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE23116
Gene Expression Omnibus
Microarray analysis of gene expression in ATM-deficient MEFs
14
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