Small molecules which mimic ATM knockout
Canned Analysis
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General Information
AccessionDCA00021319
TitleSmall molecules which mimic ATM knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ATM knockout in the irradiated MEFs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fa96e467bea600fb9f1a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1903
Cell Typeirradiated MEFs
Gene Symbol (human)ATM
Gene Symbol (mouse)Atm
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM569460, GSM569462, GSM569464
Perturbed SamplesGSM569466, GSM569468, GSM569470
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE23116
Gene Expression Omnibus
Microarray analysis of gene expression in ATM-deficient MEFs
14
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