Small molecules which mimic EGFR OE
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021339
TitleSmall molecules which mimic EGFR OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by EGFR OE in the Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fe79e467bea600fba0ce
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:194
Cell TypeEstrogen receptor (ER) alpha positive MCF-7 breast cancer cells
Gene Symbol (human)EGFR
Gene Symbol (mouse)Egfr
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM81189, GSM81190, GSM81191
Perturbed SamplesGSM81201, GSM81202, GSM81203
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3542
Gene Expression Omnibus
Estrogen receptor alpha positive breast cancer cells response to hyperactivation of MAPK pathway
28
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.