Small molecules which reverse FGFR1 drugactivation
Canned Analysis
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General Information
AccessionDCA00021354
TitleSmall molecules which reverse FGFR1 drugactivation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FGFR1 drugactivation in the brown adipose tissue of ob/ob mice cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1efb1e467bea600fb9a98
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1928
Cell Typebrown adipose tissue of ob/ob mice
Gene Symbol (human)FGFR1
Gene Symbol (mouse)Fgfr1
Organismmouse
Perturbation Typedrugactivation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM800590, GSM800591, GSM800592, GSM800593, GSM800594, GSM800595
Perturbed SamplesGSM800596, GSM800597, GSM800598, GSM800599, GSM800600, GSM800601
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32316
Gene Expression Omnibus
FGFR1 target genes in brown adipose tissues
7
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