Small molecules which mimic GSK3B knockdown
Canned Analysis
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General Information
AccessionDCA00021363
TitleSmall molecules which mimic GSK3B knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GSK3B knockdown in the Panc-1 xenografts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23909e467bea600fbba64
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1934
Cell TypePanc-1 xenografts
Gene Symbol (human)GSK3B
Gene Symbol (mouse)Gsk3b
Organismhuman
Perturbation Typeknockdown
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM866688, GSM866689, GSM866690, GSM866691
Perturbed SamplesGSM866692, GSM866693, GSM866694
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE35351
Gene Expression Omnibus
GSK3B shRNA in Panc-1 xenografts
7
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