Small molecules which mimic CDK8 knockdown
Canned Analysis
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General Information
AccessionDCA00021365
TitleSmall molecules which mimic CDK8 knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CDK8 knockdown in the HCT116 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23913e467bea600fbba68
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1937
Cell TypeHCT116
Gene Symbol (human)CDK8
Gene Symbol (mouse)Cdk8
Organismhuman
Perturbation Typeknockdown
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM933283, GSM933284, GSM933285
Perturbed SamplesGSM933286, GSM933287, GSM933288
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE38061
Gene Expression Omnibus
Expression data from HCT116 colorectal cancer cells.
28
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