Small molecules which reverse CDK8 knockdown
Canned Analysis
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General Information
AccessionDCA00021368
TitleSmall molecules which reverse CDK8 knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CDK8 knockdown in the HCT116 in low glucose cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d238eee467bea600fbba58
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1938
Cell TypeHCT116 in low glucose
Gene Symbol (human)CDK8
Gene Symbol (mouse)Cdk8
Organismhuman
Perturbation Typeknockdown
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM933303, GSM933304, GSM933305
Perturbed SamplesGSM933306, GSM933307, GSM933308
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38061
Gene Expression Omnibus
Expression data from HCT116 colorectal cancer cells.
28
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