Small molecules which reverse JAK1 druginhibition
Canned Analysis
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General Information
AccessionDCA00021376
TitleSmall molecules which reverse JAK1 druginhibition
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by JAK1 druginhibition in the BaF3 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d233a2e467bea600fbb800
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1941
Cell TypeBaF3
Gene Symbol (human)JAK1
Gene Symbol (mouse)Jak1
Organismmouse
Perturbation Typedruginhibition
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM940262, GSM940263, GSM940264
Perturbed SamplesGSM940268, GSM940269, GSM940270
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38335
Gene Expression Omnibus
JAK2 Naive and Persitent Murine BaF3 cells infected with MPLW515L
14
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