Small molecules which reverse HNF4A KO
Canned Analysis
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General Information
AccessionDCA00021382
TitleSmall molecules which reverse HNF4A KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HNF4A KO in the Embryonic liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fe72e467bea600fba0cc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:195
Cell TypeEmbryonic liver
Gene Symbol (human)HNF4A
Gene Symbol (mouse)Hnf4a
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM69792, GSM69793, GSM69794
Perturbed SamplesGSM69795, GSM69796, GSM69797
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3126
Gene Expression Omnibus
Hepatocyte nuclear factor 4 alpha knockout effect on the embryonic liver
7
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