Small molecules which reverse BRAF overexpression
Canned Analysis
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General Information
AccessionDCA00021386
TitleSmall molecules which reverse BRAF overexpression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BRAF overexpression in the melanocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22e4de467bea600fbb5aa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1951
Cell Typemelanocytes
Gene Symbol (human)BRAF
Gene Symbol (mouse)Braf
Organismhuman
Perturbation Typeoverexpression
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1138533, GSM1138534, GSM1138535
Perturbed SamplesGSM1138536, GSM1138537, GSM1138538
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46801
Gene Expression Omnibus
Expression data from Control, Uninfected and BRAF infected cells
7
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