Small molecules which reverse CSTB KO
Canned Analysis
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General Information
AccessionDCA00021408
TitleSmall molecules which reverse CSTB KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CSTB KO in the Cerebrellum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fe6ae467bea600fba0c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlhs
CREEDS IDgene:196
Cell TypeCerebrellum
Gene Symbol (human)CSTB
Gene Symbol (mouse)Cstb
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1151355, GSM1151356, GSM1151357, GSM1151358
Perturbed SamplesGSM1151351, GSM1151352, GSM1151353, GSM1151354
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47516
Gene Expression Omnibus
Cystatin B knockout model of progressive myoclonus epilepsy: cultured cerebellar granule cells
48
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