Small molecules which mimic ULK1 knockout
Canned Analysis
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General Information
AccessionDCA00021419
TitleSmall molecules which mimic ULK1 knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ULK1 knockout in the MEFs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2292be467bea600fbb364
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1965
Cell TypeMEFs
Gene Symbol (human)ULK1
Gene Symbol (mouse)Ulk1
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1488286, GSM1488287, GSM1488288
Perturbed SamplesGSM1488292, GSM1488293, GSM1488294
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE60778
Gene Expression Omnibus
Central Role of ULK1 in Type I Interferon Signaling
14
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