Small molecules which reverse ULK1 knockout
Canned Analysis
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General Information
AccessionDCA00021422
TitleSmall molecules which reverse ULK1 knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ULK1 knockout in the MEFs treated with IFNB cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2291ce467bea600fbb35e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1966
Cell TypeMEFs treated with IFNB
Gene Symbol (human)ULK1
Gene Symbol (mouse)Ulk1
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1488289, GSM1488290, GSM1488291
Perturbed SamplesGSM1488295, GSM1488296, GSM1488297
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE60778
Gene Expression Omnibus
Central Role of ULK1 in Type I Interferon Signaling
14
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