Small molecules which mimic DES KO
Canned Analysis
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General Information
AccessionDCA00021433
TitleSmall molecules which mimic DES KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DES KO in the young skeletal muscles cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1feb0e467bea600fba0e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlhs
CREEDS IDgene:198
Cell Typeyoung skeletal muscles
Gene Symbol (human)DES
Gene Symbol (mouse)Des
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM848131, GSM848132, GSM848133, GSM848134, GSM848135
Perturbed SamplesGSM848141, GSM848142, GSM848143, GSM848144, GSM848145
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE34388
Gene Expression Omnibus
Desmin deficiency effect on young and adult skeletal muscles
14
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