Small molecules which reverse DES KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021434
TitleSmall molecules which reverse DES KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DES KO in the young skeletal muscles cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1feb2e467bea600fba0e8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlhs
CREEDS IDgene:198
Cell Typeyoung skeletal muscles
Gene Symbol (human)DES
Gene Symbol (mouse)Des
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM848131, GSM848132, GSM848133, GSM848134, GSM848135
Perturbed SamplesGSM848141, GSM848142, GSM848143, GSM848144, GSM848145
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34388
Gene Expression Omnibus
Desmin deficiency effect on young and adult skeletal muscles
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.