Small molecules which mimic DES depletion (at 12-14 month old)
Canned Analysis
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General Information
AccessionDCA00021435
TitleSmall molecules which mimic DES depletion (at 12-14 month old)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DES depletion (at 12-14 month old) in the tibialis anterior muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20c30e467bea600fba6d8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:3048
Cell Typetibialis anterior muscle
Gene Symbol (human)DES
Gene Symbol (mouse)Des
Organismmouse
Perturbation Typedepletion (at 12-14 month old)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM848136, GSM848137, GSM848138, GSM848139
Perturbed SamplesGSM848146, GSM848147, GSM848148, GSM848149
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34388
Gene Expression Omnibus
Desmin deficiency effect on young and adult skeletal muscles
14
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