Small molecules which reverse BRD4 knockdown
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021444
TitleSmall molecules which reverse BRD4 knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BRD4 knockdown in the spindle cell malignant peripheral nerve sheath tumor cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21ea8e467bea600fbaec6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1985
Cell Typespindle cell malignant peripheral nerve sheath tumor cells
Gene Symbol (human)BRD4
Organismmouse
Perturbation Typeknockdown
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1231298, GSM1231299, GSM1231300
Perturbed SamplesGSM1231301, GSM1231302, GSM1231303
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50865
Gene Expression Omnibus
Expression Data For BRD4 Inhibition
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.