Small molecules which mimic BRD4 druginhibition
Canned Analysis
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General Information
AccessionDCA00021445
TitleSmall molecules which mimic BRD4 druginhibition
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by BRD4 druginhibition in the spindle cell malignant peripheral nerve sheath tumor cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21eaee467bea600fbaec8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1986
Cell Typespindle cell malignant peripheral nerve sheath tumor cells
Gene Symbol (human)BRD4
Organismmouse
Perturbation Typedruginhibition
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1231304, GSM1231305, GSM1231306
Perturbed SamplesGSM1231307, GSM1231308, GSM1231309
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50865
Gene Expression Omnibus
Expression Data For BRD4 Inhibition
14
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