Small molecules which reverse EPHA4 drugactivation
Canned Analysis
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General Information
AccessionDCA00021456
TitleSmall molecules which reverse EPHA4 drugactivation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EPHA4 drugactivation in the keratinocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21802e467bea600fbac0e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1991
Cell Typekeratinocytes
Gene Symbol (human)EPHA4
Gene Symbol (mouse)Epha4
Organismhuman
Perturbation Typedrugactivation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM652199, GSM652202, GSM652205, GSM652208
Perturbed SamplesGSM652201, GSM652204, GSM652207, GSM652210
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26523
Gene Expression Omnibus
Transcriptional targets of EphB2 and Ephrin-A4 signaling in epidermal keratinocytes
14
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