Small molecules which reverse MET knockout
Canned Analysis
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General Information
AccessionDCA00021474
TitleSmall molecules which reverse MET knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MET knockout in the liver tissue, n-nitrosodiethylamine treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f2d6e467bea600fb9bf8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2006
Cell Typeliver tissue, n-nitrosodiethylamine treatment
Gene Symbol (human)MET
Gene Symbol (mouse)Met
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM217219, GSM217221, GSM217223, GSM217229, GSM217230
Perturbed SamplesGSM217226, GSM217228, GSM217231, GSM217232, GSM217233
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8747
Gene Expression Omnibus
DEN-induced HCC in c-Met knockout mice
28
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