Small molecules which mimic MET knockout
Canned Analysis
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General Information
AccessionDCA00021477
TitleSmall molecules which mimic MET knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MET knockout in the liver tissue, n-nitrosodiethylamine treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f30de467bea600fb9c0e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2008
Cell Typeliver tissue, n-nitrosodiethylamine treatment
Gene Symbol (human)MET
Gene Symbol (mouse)Met
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM217200, GSM217202, GSM217204, GSM217206, GSM217208
Perturbed SamplesGSM217210, GSM217214, GSM217215, GSM217217
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8747
Gene Expression Omnibus
DEN-induced HCC in c-Met knockout mice
28
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