Small molecules which mimic MOK knockout
Canned Analysis
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General Information
AccessionDCA00021483
TitleSmall molecules which mimic MOK knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MOK knockout in the aorta, diabetic, ApoE KO cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23c5ae467bea600fbbbd8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2010
Cell Typeaorta, diabetic, ApoE KO
Gene Symbol (human)MOK
Gene Symbol (mouse)Mok
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM379380, GSM385478, GSM389764, GSM389765
Perturbed SamplesGSM392018, GSM392019, GSM392020, GSM392021
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15729
Gene Expression Omnibus
Receptor for AGE (RAGE) deletion effect on ApoE null mice: aorta
14
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