Small molecules which reverse RET knockout
Canned Analysis
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General Information
AccessionDCA00021488
TitleSmall molecules which reverse RET knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RET knockout in the embryonic kidney cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23c4be467bea600fbbbd2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2013
Cell Typeembryonic kidney
Gene Symbol (human)RET
Gene Symbol (mouse)Ret
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM795584, GSM795585, GSM795586
Perturbed SamplesGSM795587, GSM795588, GSM795589
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32093
Gene Expression Omnibus
Expression data from E12.5 embryonic kidneys isolated from wild-type and Ret-deficient mice
7
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