Small molecules which mimic SRC overexpression
Canned Analysis
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General Information
AccessionDCA00021489
TitleSmall molecules which mimic SRC overexpression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SRC overexpression in the primary prostate epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23c6ce467bea600fbbbe2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2014
Cell Typeprimary prostate epithelial cells
Gene Symbol (human)SRC
Gene Symbol (mouse)Src
Organismmouse
Perturbation Typeoverexpression
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM919075, GSM919076, GSM919077
Perturbed SamplesGSM919091, GSM919093, GSM919095
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37428
Gene Expression Omnibus
Gene expression data from oncogene transformed murine prostate epithelial cell lines
7
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