Small molecules which reverse SRC overexpression
Canned Analysis
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General Information
AccessionDCA00021492
TitleSmall molecules which reverse SRC overexpression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SRC overexpression in the MEFs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23c65e467bea600fbbbde
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2015
Cell TypeMEFs
Gene Symbol (human)SRC
Gene Symbol (mouse)Src
Organismmouse
Perturbation Typeoverexpression
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM378662, GSM378663, GSM378664, GSM378665, GSM378666, GSM378667, GSM378668, GSM378669, GSM378670
Perturbed SamplesGSM378680, GSM378681, GSM378682, GSM378683, GSM378684, GSM378685, GSM378686, GSM378687
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15161
Gene Expression Omnibus
Expression data from retroviral vector-infected immortalized mouse embryonic fibroblasts (MEFs)
7
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