Small molecules which mimic SPI1 KD
Canned Analysis
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General Information
AccessionDCA00021493
TitleSmall molecules which mimic SPI1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SPI1 KD in the Preleukemic hematopoietic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2004ae467bea600fba19a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:202
Cell TypePreleukemic hematopoietic stem cells
Gene Symbol (human)SPI1
Gene Symbol (mouse)Spi1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM132382, GSM132383, GSM132384
Perturbed SamplesGSM132385, GSM132386, GSM132387
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5654
Gene Expression Omnibus
Transcription factor PU.1 knockdown effect on hematopoietic stem cells
7
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