Small molecules which mimic TRIM24 knockout
Canned Analysis
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General Information
AccessionDCA00021509
TitleSmall molecules which mimic TRIM24 knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TRIM24 knockout in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2315ce467bea600fbb700
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2031
Cell Typeliver
Gene Symbol (human)TRIM24
Gene Symbol (mouse)Trim24
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM491317, GSM491318, GSM491319, GSM491320, GSM491321
Perturbed SamplesGSM491322, GSM491323, GSM491324, GSM491325, GSM491326
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE19675
Gene Expression Omnibus
Negative regulation of the IFN/STAT signaling pathway by the Trim24 tumor suppressor protein through Rara inhibition
7
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