Small molecules which reverse GSK3B KD
Canned Analysis
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General Information
AccessionDCA00021536
TitleSmall molecules which reverse GSK3B KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GSK3B KD in the HL-60 acute myeloid leukemia cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20028e467bea600fba18c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:206
Cell TypeHL-60 acute myeloid leukemia cell line
Gene Symbol (human)GSK3B
Gene Symbol (mouse)Gsk3b
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM863392, GSM863393, GSM863394
Perturbed SamplesGSM863395, GSM863396, GSM863397, GSM863398
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35200
Gene Expression Omnibus
Glycogen synthase kinase 3 knockdown in acute myeloid leukemia cell lines
70
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