Small molecules which reverse GSK3A KD
Canned Analysis
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General Information
AccessionDCA00021538
TitleSmall molecules which reverse GSK3A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GSK3A KD in the MOLM-14 myeloid leukemia cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20020e467bea600fba188
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:207
Cell TypeMOLM-14 myeloid leukemia cell line
Gene Symbol (human)GSK3A
Gene Symbol (mouse)Gsk3a
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM863414, GSM863415, GSM863416
Perturbed SamplesGSM863421, GSM863422, GSM863423, GSM863424
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35200
Gene Expression Omnibus
Glycogen synthase kinase 3 knockdown in acute myeloid leukemia cell lines
70
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