Small molecules which mimic GSK3A KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021541
TitleSmall molecules which mimic GSK3A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GSK3A KD in the THP-1 acute myeloid leukemia cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20066e467bea600fba1a6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:209
Cell TypeTHP-1 acute myeloid leukemia cell line
Gene Symbol (human)GSK3A
Gene Symbol (mouse)Gsk3a
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM863403, GSM863404, GSM863405
Perturbed SamplesGSM863410, GSM863411, GSM863412, GSM863413
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE35200
Gene Expression Omnibus
Glycogen synthase kinase 3 knockdown in acute myeloid leukemia cell lines
70
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.