Small molecules which mimic TGFBR2 knockout
Canned Analysis
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General Information
AccessionDCA00021563
TitleSmall molecules which mimic TGFBR2 knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TGFBR2 knockout in the posterior palate cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2225fe467bea600fbb064
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2063
Cell Typeposterior palate
Gene Symbol (human)TGFBR2
Gene Symbol (mouse)Tgfbr2
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1126420, GSM1126421, GSM1126422, GSM1126423, GSM1126424, GSM1126425
Perturbed SamplesGSM1126426, GSM1126427, GSM1126428, GSM1126429, GSM1126430, GSM1126431
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE46211
Gene Expression Omnibus
Transforming growth factor, beta receptor II knockout effect on embryonic posterior palate
7
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