Small molecules which reverse KLF4 OE
Canned Analysis
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General Information
AccessionDCA00021570
TitleSmall molecules which reverse KLF4 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KLF4 OE in the rko cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21c90e467bea600fbadde
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2071
Cell Typerko
Gene Symbol (human)KLF4
Gene Symbol (mouse)Klf4
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM69661, GSM69669, GSM69670, GSM69671, GSM69672, GSM69673, GSM69674, GSM69675
Perturbed SamplesGSM69662, GSM69663, GSM69664, GSM69665, GSM69666, GSM69667, GSM69668
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3113
Gene Expression Omnibus
Transgenic Krppel-like factor 4 induction: time course
7
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