Small molecules which mimic HSF1 KD
Canned Analysis
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General Information
AccessionDCA00021583
TitleSmall molecules which mimic HSF1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HSF1 KD in the HeLa cells - 0.5 Hour by siHSF1_1 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2158fe467bea600fbaaf4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:778
Cell TypeHeLa cells - 0.5 Hour by siHSF1_1
Gene Symbol (human)HSF1
Gene Symbol (mouse)Hsf1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM84604, GSM84605, GSM84606
Perturbed SamplesGSM84572, GSM84573, GSM84574
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3697
Gene Expression Omnibus
Heat shock transcription factor HSF1 depleted cells response to heat shock: time course
63
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