Small molecules which reverse NOD2 VR
Canned Analysis
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General Information
AccessionDCA00021598
TitleSmall molecules which reverse NOD2 VR
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NOD2 VR in the hek293 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21024e467bea600fba89a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2096
Cell Typehek293
Gene Symbol (human)NOD2
Gene Symbol (mouse)Nod2
Organismhuman
Perturbation TypeVR
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM560855, GSM560856, GSM560857
Perturbed SamplesGSM560858, GSM560859, GSM560860
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22611
Gene Expression Omnibus
Bacterial cell wall component MDP effect on HEK293 cells expressing Crohn's disease-associated NOD2 variant L1007fsinsC receptor: time course
7
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