Small molecules which mimic CEBPA VR
Canned Analysis
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General Information
AccessionDCA00021599
TitleSmall molecules which mimic CEBPA VR
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CEBPA VR in the pbmc cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21018e467bea600fba894
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2097
Cell Typepbmc
Gene Symbol (human)CEBPA
Gene Symbol (mouse)Cebpa
Organismhuman
Perturbation TypeVR
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM822463, GSM822464, GSM822465, GSM822466, GSM822467, GSM822468, GSM822469, GSM822470, GSM822471, GSM822472
Perturbed SamplesGSM822473, GSM822474, GSM822475, GSM822476, GSM822477, GSM822478, GSM822479, GSM822480, GSM822481
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33223
Gene Expression Omnibus
Biallelic CEBPA-mutated acute myeloid leukemia with multilineage dysplasia: peripheral blood mononuclear cells
7
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