Small molecules which mimic HSF1 KO
Canned Analysis
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General Information
AccessionDCA00021609
TitleSmall molecules which mimic HSF1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HSF1 KO in the Tcell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23296e467bea600fbb788
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2143
Cell TypeTcell
Gene Symbol (human)HSF1
Gene Symbol (mouse)Hsf1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1006698, GSM1006699
Perturbed SamplesGSM1006700, GSM1006701
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE41005
Gene Expression Omnibus
HSF1 mediated Gene regulation in T cells at normal (37C) and febrile (40C) temperatures
7
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