Small molecules which mimic TET1 KD
Canned Analysis
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General Information
AccessionDCA00021611
TitleSmall molecules which mimic TET1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TET1 KD in the mesc_v6.5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d232b0e467bea600fbb794
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2146
Cell Typemesc_v6.5
Gene Symbol (human)TET1
Gene Symbol (mouse)Tet1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM662485, GSM662486, GSM662487
Perturbed SamplesGSM662488, GSM662489, GSM662490
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE26900
Gene Expression Omnibus
Effect of Tet1-knockdown on gene expression in mouse ES cells cultured in ES and TS cell culture conditions
7
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