Small molecules which reverse EOMES KO
Canned Analysis
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General Information
AccessionDCA00021614
TitleSmall molecules which reverse EOMES KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EOMES KO in the E14dot5_neocortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d232aae467bea600fbb792
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2147
Cell TypeE14dot5_neocortex
Gene Symbol (human)EOMES
Gene Symbol (mouse)Eomes
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1061846, GSM1061847, GSM1061849, GSM1061850, GSM1061851
Perturbed SamplesGSM1061845, GSM1061848, GSM1061852
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE43387
Gene Expression Omnibus
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map
7
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