Small molecules which mimic UPF1 Deficiency
Canned Analysis
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General Information
AccessionDCA00021617
TitleSmall molecules which mimic UPF1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by UPF1 Deficiency in the HeLa cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f9d5e467bea600fb9ec6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:215
Cell TypeHeLa cells
Gene Symbol (human)UPF1
Gene Symbol (mouse)Upf1
Organismhuman
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM161670, GSM161671, GSM161674
Perturbed SamplesGSM161678, GSM161679, GSM161686
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7009
Gene Expression Omnibus
Nonsense mediated decay factor UPF1 depletion
7
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