Small molecules which mimic WT1 KO
Canned Analysis
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General Information
AccessionDCA00021629
TitleSmall molecules which mimic WT1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by WT1 KO in the Mouse_Embryonic_Fibroblast_MEF cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23801e467bea600fbb9ee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2156
Cell TypeMouse_Embryonic_Fibroblast_MEF
Gene Symbol (human)WT1
Gene Symbol (mouse)Wt1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM446988, GSM449564, GSM449565, GSM449566, GSM449567
Perturbed SamplesGSM384909, GSM384910, GSM446979, GSM446981, GSM446984
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15325
Gene Expression Omnibus
MEF-mKras-WT1
7
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