Small molecules which reverse CREB1 DN
Canned Analysis
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General Information
AccessionDCA00021632
TitleSmall molecules which reverse CREB1 DN
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CREB1 DN in the heart_left_ventricle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23816e467bea600fbb9f8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2158
Cell Typeheart_left_ventricle
Gene Symbol (human)CREB1
Gene Symbol (mouse)Creb1
Organismmouse
Perturbation TypeDN
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM435921, GSM435922, GSM435923
Perturbed SamplesGSM435927, GSM435928, GSM435929
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE17478
Gene Expression Omnibus
Particulate matter effect on dilated cardiomyopathy model: lung and heart
14
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