Small molecules which reverse CREB1 DN
Canned Analysis
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General Information
AccessionDCA00021634
TitleSmall molecules which reverse CREB1 DN
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CREB1 DN in the lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2238ae467bea600fbb0e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2199
Cell Typelung
Gene Symbol (human)CREB1
Gene Symbol (mouse)Creb1
Organismmouse
Perturbation TypeDN
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM435909, GSM435910, GSM435911
Perturbed SamplesGSM435915, GSM435916, GSM435917
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17478
Gene Expression Omnibus
Particulate matter effect on dilated cardiomyopathy model: lung and heart
14
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