Small molecules which mimic CDKN1B KO
Canned Analysis
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General Information
AccessionDCA00021661
TitleSmall molecules which mimic CDKN1B KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CDKN1B KO in the mouse_embryonic_fibroblast_MEF cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20bf0e467bea600fba6bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2178
Cell Typemouse_embryonic_fibroblast_MEF
Gene Symbol (human)CDKN1B
Gene Symbol (mouse)Cdkn1b
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM685400, GSM685401, GSM685402
Perturbed SamplesGSM685406, GSM685407, GSM685408
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27672
Gene Expression Omnibus
Expression data from p27WT, p27CK and KO MEFs cells in quiescence
7
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