Small molecules which reverse CDKN1B KO
Canned Analysis
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General Information
AccessionDCA00021664
TitleSmall molecules which reverse CDKN1B KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CDKN1B KO in the 3T3 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f3d0e467bea600fb9c64
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2179
Cell Type3T3
Gene Symbol (human)CDKN1B
Gene Symbol (mouse)Cdkn1b
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM231384, GSM231409, GSM231417
Perturbed SamplesGSM231405, GSM231414, GSM231425
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9161
Gene Expression Omnibus
Expression profiling of cyclin D1 splice variants cyclin D1a and D1b in mouse 3T3 cells.
7
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