Small molecules which reverse CTNNB1 VR
Canned Analysis
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General Information
AccessionDCA00021666
TitleSmall molecules which reverse CTNNB1 VR
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 VR in the adrenocortical_adenomas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21db0e467bea600fbae5a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2186
Cell Typeadrenocortical_adenomas
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeVR
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM703792, GSM703793, GSM703794, GSM703795
Perturbed SamplesGSM703789, GSM703790, GSM703791
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE28476
Gene Expression Omnibus
Adrenocortical adenomas harboring -catenin gene CTNNB1 mutations
7
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