Small molecules which mimic AR KD
Canned Analysis
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General Information
AccessionDCA00021667
TitleSmall molecules which mimic AR KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by AR KD in the LNCaP cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2236be467bea600fbb0d8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2194
Cell TypeLNCaP
Gene Symbol (human)AR
Gene Symbol (mouse)Ar
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM558624, GSM558625
Perturbed SamplesGSM558628, GSM558629
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22483
Gene Expression Omnibus
Late passage LNCaP prostate tumor cells treated with androgen receptor shRNA or androgen R1881
7
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