Small molecules which reverse NR2C2 KO
Canned Analysis
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General Information
AccessionDCA00021684
TitleSmall molecules which reverse NR2C2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NR2C2 KO in the liver_1yo cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2233fe467bea600fbb0c6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2200
Cell Typeliver_1yo
Gene Symbol (human)NR2C2
Gene Symbol (mouse)Nr2c2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM544786, GSM544787, GSM544788, GSM544789, GSM544790
Perturbed SamplesGSM544791, GSM544792, GSM544793, GSM544794, GSM544795
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21903
Gene Expression Omnibus
Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance
7
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