Small molecules which mimic SETDB1 KO
Canned Analysis
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General Information
AccessionDCA00021695
TitleSmall molecules which mimic SETDB1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SETDB1 KO in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22320e467bea600fbb0b8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:2205
Cell TypeES cells
Gene Symbol (human)SETDB1
Gene Symbol (mouse)Setdb1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM707696, GSM707697, GSM707698
Perturbed SamplesGSM707699, GSM707700, GSM707701
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE28593
Gene Expression Omnibus
KMT1E Mediated H3K9 Methylation Is Required for the Maintenance of Embryonic Stem Cells by Repressing Trophectoderm Differentiation
7
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