Small molecules which mimic LAMC2 KD
Canned Analysis
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General Information
AccessionDCA00021699
TitleSmall molecules which mimic LAMC2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LAMC2 KD in the TL3 Anaplastic thyroid carcinoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21d80e467bea600fbae44
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2210
Cell TypeTL3 Anaplastic thyroid carcinoma
Gene Symbol (human)LAMC2
Gene Symbol (mouse)Lamc2
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1228818, GSM1228819, GSM1228820
Perturbed SamplesGSM1228821, GSM1228822, GSM1228823
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50767
Gene Expression Omnibus
Anaplastic thyroid carcinoma cell lines (HTH83 and TL3) infected with LAMC2 shRNA
14
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