Small molecules which mimic ARF1 KD
Canned Analysis
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General Information
AccessionDCA00021701
TitleSmall molecules which mimic ARF1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ARF1 KD in the cell line: MDA-MB-231 breast cancer cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22358e467bea600fbb0d0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2209
Cell Typecell line: MDA-MB-231 breast cancer cell line
Gene Symbol (human)ARF1
Gene Symbol (mouse)Arf1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1192049, GSM1192050, GSM1192051
Perturbed SamplesGSM1192052, GSM1192053, GSM1192054, GSM1192055, GSM1192056, GSM1192057, GSM1192058, GSM1192059, GSM1192060
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49005
Gene Expression Omnibus
Multiscale Gene Networks Dissect the Complexity of Breast Cancer
7
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